you mean similar to
this but then you need a guider scope. if you don't have better try with a piggy back 50mm guider scope. you can take many 30 sec shots like saudara redzuan's M42 and stack them. More bang for the buck.

maybe you are thinking like
this . The black mount is a clone of EQ6.
Full frame Canon 5D2 with 50mm. Most agree than best performance to price for 50mm is the Sigma f1.4 followed by Canon's from 1.8 to 1.4 to 50mm f1.2L. Nikkor's wide angle are superior so best if you seek Nikkor Ais and get EOS adapter
I have seen images using Sigma lense. Google and
here is one.
If there is coma and corner softness I don't see any.

Canon 50mm f1.8 is cheap. So why not try. Add to total sum of knowledge in amateur astronomy.

cheers